Vitamin A status and the metabolism of cholesterol in the rat

Abstract

1. The interrelationship between cholesterol and vitamin A metabolism has been studied in rats.2. The effect of cholesterol feeding in increasing the liver storage of cholesterol w-as enhanced during vitamin A deficiency.3. This effect was due to an increased rate of absorption of cholesterol and not due to a decreased turnover rate.4. Feeding of high levels of vitamin A markedly depressed the cholesterol absorption; however, its turnover was unaffected.