STUDY OF BOVINE PULMONARY RESPONSE TO PASTEURELLA-HAEMOLYTICA - SPECIFICITY OF IMMUNOGLOBULINS ISOLATED FROM THE BOVINE LUNG

  • 1 January 1980
    • journal article
    • research article
    • Vol. 41 (7), 1015-1023
Abstract
A procedure is described for the isolation and purification of immunoglobulin(Ig)A and IgG from pulmonary lavage fluid from calves. These Ig were isolated from calves experimentally exposed to P. haemolytica via aerosolization and from non-exposed calves. The specificity of these fractions toward P. haemolytica was examined, using an indirect fluorescent antibody test and agglutination reactions. Specific antibody activity was detected in the IgA and IgG fractions from calves exposed to P. haemolytica and IgG fractions from non-exposed calves. None of the isolated Ig agglutinated P. haemolytica.