THE ROLE OF EXOGENOUS LIPIDS IN THE HYPERLIPEMIA AND HYPERCHOLESTEREMIA OF NEPHROTIC RATS 1
Open Access
- 1 August 1954
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 33 (8), 1103-1105
- https://doi.org/10.1172/jci102983
Abstract
The development of hyper-lipemia and hypercholesteremia was studied in nephrotic rats fed a normal diet, a ration free of fats and sterols, and a ration supplemented with cholesterol and cholic acid. The results indicate that the development and maintenance of hyperlipemia and hypercholesteremia in the nephrotic rat are of endogenous origin and that increased retention of lipids occurs in the plasma of such rats. It is suggested that the hyperlipemia and hypercholesteremia of nephrotic rats are due to a diminished rate of elimination of lipids from their plasma.Keywords
This publication has 10 references indexed in Scilit:
- Intestinal Absorption of Cholesterol by the Nephrotic RatCirculation Research, 1954
- Role of Cholate in Dietary-Induced Hypercholesteremia of Rats and RabbitsAmerican Journal of Physiology-Legacy Content, 1953
- OBSERVATIONS CONCERNING THE PRODUCTION AND EXCRETION OF CHOLESTEROL IN MAMMALSThe Journal of Experimental Medicine, 1953
- OBSERVATIONS CONCERNING THE CHOLATE: CHOLESTEROL RELATIONSHIP IN CLINICAL AND EXPERIMENTAL NEPHROSIS 12JCI Insight, 1953
- Induced Hypercholesterolemia and AtherogenesisCirculation, 1952
- Production and Excretion of Cholesterol in MammalsAmerican Journal of Physiology-Legacy Content, 1952
- REVIEW - ON THE REGULATION OF BLOOD CHOLESTEROL1952
- COLORIMETRIC DETERMINATION OF BLOOD LIPIDESJournal of Biological Chemistry, 1951
- NEPHROTIC SYNDROME IN RATS1951
- OBSERVATIONS CONCERNING THE PRODUCTION AND EXCRETION OF CHOLESTEROL IN MAMMALS .1. PLASMA CHOLESTEROL AFTER BILE DUCT LIGATION AND FREE CHOLESTEROL INJECTION1950