THE ROLE OF EXOGENOUS LIPIDS IN THE HYPERLIPEMIA AND HYPERCHOLESTEREMIA OF NEPHROTIC RATS 1
Open Access
- 1 August 1954
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 33 (8), 1103-1105
- https://doi.org/10.1172/jci102983
Abstract
The development of hyper-lipemia and hypercholesteremia was studied in nephrotic rats fed a normal diet, a ration free of fats and sterols, and a ration supplemented with cholesterol and cholic acid. The results indicate that the development and maintenance of hyperlipemia and hypercholesteremia in the nephrotic rat are of endogenous origin and that increased retention of lipids occurs in the plasma of such rats. It is suggested that the hyperlipemia and hypercholesteremia of nephrotic rats are due to a diminished rate of elimination of lipids from their plasma.This publication has 10 references indexed in Scilit:
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