Reliability of Histo‐Pathological Diagnosis of Squamous Epithelial Changes of The Uterine Cervix

Abstract
The reliability of histological diagnosis of squamous epithelial changes was tested by letting 13 pathologists read 1001 cervical biopsies twice. Intraobserver and interobserver agreement, variance and deviation of diagnosis were determined. The diagnostic ability showed great individual variation and no significant correlation to experience in pathology. The diagnosis of invasive cancer had a high specificity, and the diagnostic sensitivity of no significant epithelial changes was also high. The reliability of the diagnosis of dysplasia and carcinoma in situ proved unsatisfactory.