RNA CODEWORDS AND PROTEIN SYNTHESIS, II. NUCLEOTIDE SEQUENCE OF A VALINE RNA CODEWORD
- 1 August 1964
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 52 (2), 420-427
- https://doi.org/10.1073/pnas.52.2.420
Abstract
The binding of C14-valine-sRNA to ribosomes was directed both by the trinucleotide, GpUpU, and by poly UG, but not by UpGpU, UpUpG, or dinucleotides. GpUpU had no effect upon the binding to ribosomes of sRNA corresponding to 17 other amino acids. The nucleotide sequence GpUpU was proposed for a valine RNA codeword. The implications of these findings and predictions based on amino acid replacement data are discussed briefly.Keywords
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