The Bacterial Factor in Traumatic Shock

Abstract

IN a standardized preparation of hemorrhagic shock we have repeatedly demonstrated that over 80 per cent of animals recover promptly and completely if the blood lost is returned after ninety minutes, but not if return is delayed four hours or longer.¹ The literature discloses no biochemical change peculiar to shock by which one can distinguish between an early and a late stage of shock.² But a pathologic change characteristic of late shock is hemorrhagic necrosis of the intestinal mucosa or focal hemorrhages in the wall of the intestine, or both. This lesion, as Delaunay and his co-workers³ and others⁴ have . . .