Abstract
Strepto-kinase -activated human globulin, and globulin isolated from spontaneously active human blood are potent activators of plasminogen. Fibrinolysis produced by activation of plasminogen in a bovine fibrin substrate by these prepns. was increased considerably by di- and tri-carboxylic acids and decreased by diaminomonocarboxylic acids. Fibrinolytic activity of bovine plasmin and some other proteases was generally not significantly influenced; bovine plasmin was moderately inhibited by lysine.