THE FUNCTIONAL EFFECT OF EXPLANTING ONE KIDNEY AND REMOVING THE OTHER

Abstract

Explantation of one kidney, while the other was left in situ, caused no change in the urea clearance of dogs. After removal of the nonexplanted kidney, the av. urea clearance decreased, not to 50%, but to 64% of the original, indicating an increase in the functional activity of the remaining kidney, apparent during the first wks. after the unilateral nephrectomy. Subsequently the clearance of the single, explanted kidney, during observation up to 2 yrs., either remained constant or tended to increase.