A MUTANT OF YEAST APPARENTLY DEFECTIVE IN THE INITIATION OF PROTEIN SYNTHESIS
- 1 February 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 62 (2), 468-474
- https://doi.org/10.1073/pnas.62.2.468
Abstract
A temperature-sensitive mutant of yeast, ts(-)187, which is apparently unable to initiate the synthesis of new polypeptide chains after a short incubation at the restrictive temperature, is described. The existence of this mutant demonstrates that in eucaryotic cells, as in procaryotic cells, there are processes unique to the initiation of polypeptide chains.Keywords
This publication has 6 references indexed in Scilit:
- Role of a protein factor in the functional binding of ribosomes to natural messenger RNAJournal of Molecular Biology, 1968
- Macromolecule Synthesis in Yeast SpheroplastsJournal of Bacteriology, 1967
- Initiation of polyphenylalanine synthesis by N-acetylphenylalanyl-SRNA.Proceedings of the National Academy of Sciences, 1967
- TRANSLATION OF THE GENETIC MESSAGE, II. EFFECT OF INITIATION FACTORS ON THE BINDING OF FORMYL-METHIONYL-TRNA TO RIBOSOMESProceedings of the National Academy of Sciences, 1967
- N-Formyl-Methionyl-sRibonucleic Acid and Chain Initiation in Protein Biosynthesis: Polypeptide Synthesis Directed by a Bacteriophage Ribonucleic Acid in a Cell-Free SystemNature, 1966
- A GENETIC LOCUS FOR THE REGULATION OF RIBONUCLEIC ACID SYNTHESISProceedings of the National Academy of Sciences, 1961