WEIBEL-PALADE BODIES IN ENDOTHELIAL-CELLS AS A MARKER FOR ANGIOGENESIS IN BRAIN-TUMORS
- 1 January 1980
- journal article
- research article
- Vol. 40 (6), 2010-2019
Abstract
A transmission electron microscope study was made of 8 childhood brain tumors divided up into 3 zones.sbd.center, edge, infiltrating zone.sbd.and also of adjacent normal-looking brain. In 7 of 8 tumors, the numbers of Weibel-Palade bodies in endothelial cells were significantly increased in peripheral zones compared with central zones. A similar significant increase was observed after treatment of chick chorioallantoic membranes with tumor angiogenesis factor. Large numbers of Weibel-Palade bodies may be a marker for proliferating endothelial cells in vivo.This publication has 8 references indexed in Scilit:
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