Ascites Production in 17 Mouse Strains

Abstract
Mouse strains vary in their production of ascitic fluid. Intraperitoneal injections of heat-killed Staphylococcus aureus-incomplete Freund''s adjuvant mixtures induce early development of ascites. Yield of ascitic fluid may be greater with adjuvant alone but production is often delayed. High late yield for BALB/cAnN mice receiving only adjuvant are associated with occurrence of plasma cell tumors.