Transport and accumulation of purine bases by Crithidia fasciculata
- 1 August 1978
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 96 (2), 165-170
- https://doi.org/10.1002/jcp.1040960205
Abstract
The capacity for the rapid transport of purine bases by Crithidia fasciculata is found only in cells starved for purines. Cells grown in complete medium transport poorly. Rapid transport capability appears and then disappears during growth of purine-depleted cultures. This rapid transport appears to occur by a process of mediated diffusion. Two mechanisms are involved, one of low velocity and high affinity, the other of high velocity and low affinity. Accumulation of the bases within the cell occurs by their rapid conversion to ribonucleotides by phosphoribosyltransferases.This publication has 19 references indexed in Scilit:
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