Actin-Myosin Interaction: Inhibition of the Myosin Adenosine Triphosphatase by Actin
- 25 March 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 151 (3717), 1541-1542
- https://doi.org/10.1126/science.151.3717.1541
Abstract
In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. This finding suggests that both effects result from a conformational change in the active site of the myosin adenosine triphosphatase.Keywords
This publication has 14 references indexed in Scilit:
- Dissociation of a Complex of F-Actin and H-Meromyosin by Addition of Adenosine Triphosphate*The Journal of Biochemistry, 1965
- The action of thiol inhibitors on the interaction of F-actin and heavy meromyosinBiochemical Journal, 1964
- Modification of L-myosin by disulfide-sulfhydryl interchange reactionBiochimica et Biophysica Acta (BBA) - General Subjects, 1964
- On the interaction between myosin A and F-actinBiochimica et Biophysica Acta (BBA) - General Subjects, 1964
- The optical rotatory dispersion of myosin a IV. Conformational changes in meromyosinsBiochimica et Biophysica Acta, 1963
- Chemistry of Muscle Contraction: Adenosine Triphosphate and Phosphorylcreatine as Energy Supplies for Single Contractions of Working MuscleNature, 1962
- Interaction of Actomyosin with Adenosine Triphosphate at Low Ionic StrengthPublished by Elsevier ,1962
- The association constant of the complexes of adenosine triphosphate with magnesium, calcium, strontium, and barium ionsBiochimica et Biophysica Acta, 1961
- Die erschöpfende reinigung von aktin-präparaten zahl und art der phosphathaltigen prosthetischen gruppen von G- und F-aktinBiochimica et Biophysica Acta, 1960
- Die Umwandlung von Aktomyosin-ATPase in L-Myosin-ATPase durch Aktivatoren und die resultierenden AktivierungseffekteZeitschrift für Naturforschung B, 1952