Heterosubstituted anthracene-9,10-dione analogs. The synthesis and antitumor evaluation of 5,8-bis[(aminoalkyl)amino]naphtho[2,3-b]thiophene-4,9-diones
- 1 September 1990
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 33 (9), 2651-2655
- https://doi.org/10.1021/jm00171a048
Abstract
A number of 5,8-bis[(aminoalkyl)amino]naphtho[2,3-b]thiophene-4,9-diones have been synthesized and evaluated for antitumor activity against L1210 leukemia both in vitro and in vivo. Two of the congeners exhibited in vivo activities quite comparable to that of mitoxantrone.This publication has 39 references indexed in Scilit:
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