Effect on Human Serum Lipids of Substituting Plant for Animal Fat in Diet.

Abstract
Six subjects with obesity of exogenous origin showed significant reductions in serum concentrations of free and esterified cholesterol and of phospholipids when plant fats were substituted isocalorically for animal fats during a 4-month metabolic ward study. The approximate magnitude of the change was a 20% decrease. Neutral fat levels shows no significant change. Body weights and caloric intakes were held constant throughout the experiment.