The Effects of Guanethidine on the Noradrenaline Content of the Hypothalamus in the Cat and Rat
- 31 August 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (1), 518-521
- https://doi.org/10.1111/j.2042-7158.1963.tb12827.x
Abstract
Single injections of guanethidine 15 mg./kg. i.p. did not lower the hypothalamic noradrenaline in cats, but, daily injections of 15 mg./kg. s.c. over a 7 day period consistently produced a decrease in the hypothalamic noradrenaline. Attempts to lower the hypothalamic noradrenaline in rats after single injections or daily injections of guanethidine were unsuccessful.Keywords
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