Beta Thalassemia Trait: Detection at Birth
- 9 August 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 161 (3841), 589-590
- https://doi.org/10.1126/science.161.3841.589
Abstract
The synthesis of alpha, beta, and gamma chains in samples of cord blood was measured by the incorporation of leucine labeled with carbon-14 into these chains. In a newborn affected with beta thalassemia trait, the presence of one beta thalassemia gene was revealed on the 1st day of life by the lower specific radioactivity of the beta chain.Keywords
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