Studies on Delayed (Cellular) Hypersensitivity in Mice Infected with Trichinella spiralis. III. Serologic and Histopathologic Findings in Recipients Given Peritoneal Exudate Cells

Abstract

The present results confirm those of the previous paper in this series by showing that peritoneal exudate cells transferred from infected donors cause a significant loss of adult worms in recipients given a challenging infection. In addition, the mice of these various studies were shown to be an isologous strain, and peritoneal exudate cells from uninfected donors had no demonstrable effect on worm elimination. On the basis of serologic, and, especially, intestinal histopathologic findings, additional evidence is provided to support the hypothesis that worm elimination is associated with delayed hypersensitivity.