Gene conversion in higher organisms: Non-reciprocal recombination events at the rosy cistron inDrosophila melanogaster

Abstract

SUMMARY: Analysis of a series of exceptionalry⁺half-tetrads, produced in mass matings involving rosy mutant heterozygous half-tetrads, provides rigorous demonstration of the occurrence of non-reciprocal as well as reciprocal recombination events within the rosy cistron ofDrosophila melanogaster. Inferences about allele recombination drawn from this and other studies in Drosophila provide a strong argument that gene conversion occurs as a regular event in higher eukaryotes.