Mixed Lichen Planus‐Lupus Erythematosus Disease

Abstract

Two patients were reported with clinical symptoms of systemic lupus erythematosus associated with centrally ulcerated hypertrophic plaques and lip lesions. Histological findings from various sites were features of both lupus erythematosus and lichen planus. An increase in acid mucopolysaccharides and a thickened basement membrane which were present in some biopsies were interpreted as lupus erythematosus. The deposition of immunoglobulins and fibrinogen seemed to favor lupus erythematosus but these findings may also be seen in lichen planus. Possible interpretations of the findings were discussed. The term mixed lichen planus-lupus erythematosus disease may be appropriate for these patients.