PITUITARY GLAND INFLUENCES ON WATER BALANCE IN THE RAT

Abstract

The rat did not respond as does the dog with an increased urine output to administration of beef ant. lobe extract or of ant. lobe + thyroid. The usual response of urine output of normal, of postlobeetomized and of hypophysectomized rats to administration of ant. lobe alone or with thyroid is no change or a decrease; in 1 case of 7 hypophysectomized ant. lobe + thyroid was accompanied by a large increase. Failure of increase in urine output cannot be ascribed to a failure of increase in basal metabolic rate.