A Tobacco Smoke Inhalation Exposure Device for Rodents
- 1 March 1978
- journal article
- research article
- Published by Taylor & Francis in Archives of environmental health
- Vol. 33 (2), 64-71
- https://doi.org/10.1080/00039896.1978.10667311
Abstract
A system which utilizes a piston pump to generate cigarette smoke under standard conditions, and expose rodents to the inhalation of diluted smoke for controlled periods of time is described. Variations of the basic system have been employed to expose groups of ten to twenty hamsters or rats, and should allow exposures of up to forty mice. The system has been in use for approximately 24 months in routine chronic exposures of rats. Data are presented to define the operating characteristics and typical dosimetry. Animal containment peculiar to this apparatus is described.This publication has 3 references indexed in Scilit:
- A Simplified Method for the Determination of Labeled Alkane Hydrocarbons in Mammalian Tissue and Blood After Exposure to Radiolabeled Cigarette SmokeAnalytical Letters, 1973
- Studies of Cigarette Smoke Transfer Using Radioisotopically Labelled Tobacco Constituents: Part III: The Use of Dotriacontane-16,17-14C as a Marker for the Deposition of Cigarette Smoke in the Respiratory System of ExperimentaI AnimalsContributions to Tobacco Research, 1973
- The determination of nicotine in tobacco and in particulate matter of smoke by gas chromatographyAnalytica Chimica Acta, 1968