Further Studies on Effect of Cold and Restraint on Tissue Non-Protein Sulfhydryl Compounds.

Abstract

Both hypothermia and restraint were independently capable of de-creasing the concn. of liver total non-protein sulfhydryl compounds (NPSH). When these stresses were applied simultaneously, the effect of the 2 stresses was approx. additive. No significant change of NPSH was observed in muscle or kidney. The possibility that the more immediate cause of the drop in concn. of liver NPSH was activation of the sympathoadrenal mechanism is discussed.