Abstract
The role of the kidney in the turnover of administered radioactive vitamin B12 was studied in rats. It was found that, unlike other organs, the kidney has a large capacity for storing vitamin B12 that has been absorbed in excess of the body requirement, and releases it later. The kidney also has a unique function of sparing its share when the demand for this vitamin in the body is great. The liver is very different from the kidney in this respect, and cannot be regarded as a storage organ of vitamin B12 in the same sense.