Neonatal Androgen or Estrogen Treatment and the Adrenal Cortica Response to Stress in Adult Rats1
- 1 June 1967
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 80 (6), 1177-1179
- https://doi.org/10.1210/endo-80-6-1177
Abstract
Female rats treated with androgen 120 hr after birth or estrogen 96 hr after birth exhibited normal stress-induced elevations in plasma corticosterone concentrations. Both hormones produced the expected anovulatory condition, and significantly increased adrenal and body weights. Male rats treated with androgen neonatally showed a significant increase in body weight and a slight decrease in testicularweight. No effect was observed in the adrenal cortical response to stress. Neonatal estrogen treatment did significantly elevate the response to stress in adult males. Testicular and body weights were markedly reduced but adrenal weights were increased as a function of neonatal estrogen treatment and were comparable to those of normal females. (Endocrinology80:1177,1967)Keywords
This publication has 8 references indexed in Scilit:
- EFFECTS OF A SINGLE DOSE OF TESTOSTERONE ADMINISTERED TO RATS IN EARLY POSTNATAL PERIOD ON ADRENAL FUNCTION IN ADULT LIFE1966
- Sexual differentiation of the brain and its experimental control.The Journal of Physiology, 1965
- MODIFICATION OF MALE RAT REPRODUCTIVE TRACT DEVELOPMENT BY A SINGLE INJECTION OF TESTOSTERONE PROPIONATE SHORTLY AFTER BIRTHActa Endocrinologica, 1965
- Thyroid and Adrenal Regulation in the Steroid-Sterilized RatEndocrinology, 1965
- Fluorometric Determination of Corticosterone and Cortisol in 0.02–0.05 Milliliters of Plasma or Submilligram Samples of Adrenal Tissue1Endocrinology, 1964
- Pituitary-Adrenal Function in the Rat After Gonadectomy and Gonadal Hormone Replacement1Endocrinology, 1963
- Effect of Estradiol Benzoate Treatment in the Newborn Male Rat1Endocrinology, 1963
- SEX DIFFERENCES IN ADRENAL CORTICAL SECRETION IN THE RAT1Endocrinology, 1961