Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus.
- 1 November 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 56 (5), 1594-1598
- https://doi.org/10.1073/pnas.56.5.1594
Abstract
Estrogen stimulates both the synthesis of nuclear RNA and the uptake of RNA precursor by the uterus within 2 min. following administration of the hormone to the ovariectomized adult rat. The immediacy of these effects clearly illustrates that estrogen in some unknown way stimulates membrane activity and transcription of DNA. This results in a very rapid synthesis of a few specific molecules of RNA which presumably initiate and support the subsequent stimulation of uterine protein synthesis.This publication has 8 references indexed in Scilit:
- Evidence for depression of nuclear protein synthesis and concomitant stimulation of nuclear RNA synthesis during early estrogen action.Proceedings of the National Academy of Sciences, 1966
- Estrogen-induced synthesis of a specific uterine protein.Proceedings of the National Academy of Sciences, 1966
- A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.Proceedings of the National Academy of Sciences, 1966
- Estrogen control of the synthesis of RNA and protein in the uterusJournal of Cellular and Comparative Physiology, 1965
- Sequential stimulations by oestrogen of nuclear RNA synthesis and DNA-dependent RNA polymerase activities in rat uterusBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1965
- Role of RNA in the regulatory action of estrogen.Proceedings of the National Academy of Sciences, 1965
- ROLE OF HISTAMINE IN MEDIATION OF HORMONE ACTION1965
- THE ROLE OF PROTEIN SYNTHESIS IN EARLY ESTROGEN ACTIONProceedings of the National Academy of Sciences, 1961