THE EFFECTS OF HYPOPHYSECTOMY ON GASTRIC ACIDITY OF ADULT FEMALE RATS1
- 1 June 1947
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 40 (6), 395-402
- https://doi.org/10.1210/endo-40-6-395
Abstract
HYPOPHYSECTOMY induces an anemia in adult male or female rats. This anemia is microcytic and hypochromic, accompanied by hypoplasia of the bone marrow (Crafts, 1946). Injections of a combination of thyroxine, iron, and copper alleviated the anemia (Crafts, 1946). This suggests that the metabolism of iron may be disturbed following hypophysectomy. All phases of iron metabolism are being studied in normal and hypophysectomized female rats. Normal gastric acidity is generally recognized as a significant factor in iron absorption. This paper is concerned with changes in the acidity of gastric secretion following removal of the hypophysis.Keywords
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