Pyelonephritis IV. Role of Serum Bactericidal Activity and Antibody in Chronic Enterococcal Pyelonephritis in the Rat.

Abstract
Summary Pyelonephritis produced in rats by intravenous inoculation of Str. faecalis becomes established in the presence of normal serum bactericidal activity against the infecting organism. The infection persists throughout the life of the rat despite the eventual appearance of circulating antibacterial antibodies. This finding may be partially explained by the fact that these antibodies do not enhance normal serum bactericidal activity as tested.