Immunological Relationships Between Homologous Structural Polypeptides of Measles and Canine Distemper Virus
- 1 October 1980
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 50 (2), 231-245
- https://doi.org/10.1099/0022-1317-50-2-231
Abstract
The major structural polypeptides of measles and canine distemper virus (CDV) were isolated by SDS-polyacrylamide slab gel electrophoresis. Rabbit hyperimmune sera directed against the isolated HA, P, NP, F and M polypeptides were prepared. In addition, rabbit hyperimmune sera directed against purified native internal components of measles virus and against purified virions of measles and CDV, untreated or treated with trypsin, were prepared. These sera were used to study the immunological relationships between measles and CDV in immune precipitation tests with 35S-methionine-labelled extracellular virions and intracellular virus polypeptides and by use of complement fixation and mixed haemadsorption tests.This publication has 17 references indexed in Scilit:
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