Characterization of two major neutral glyceroglucolipids of the human gastric content

Abstract

Two major neutral glyceroglucolipids (A and B) were isolated from lipid extract of human gastric content by the procedure involving column fractionation on DEAE-Sephadex, silicic acid and TLC. Both glycolipids contained glucose, glyceryl ethers and fatty acids. The structures of these glycolipids were identified by mild alkaline methanolysis, oxidation with periodate and chromium trioxide, and permethylation studies. Glycolipid A is apparently a monoalkylmonoacylglyceryl hexaglucoside, and glycolipid B is a monoalkylmonoacylglyceryl octaglucoside. The diglyceride portion of these glycolipids consists mostly of 1-O-alkyl-2-O-acylglycerol.