Some Observations of Effects of Intravenous Fat Emulsions on Erythrocyte Fragility

Abstract

Intraven. infusion of fat emulsions causes increased mechanical fragility of dog and human red blood cells. Spontaneous intravascular hemolysis has been observed in human subjects who received these emulsions. The possible causes of the phenomenon are discussed and the possible causal relationship to the febrile reactions following intraven. fat is postulated.