Characteristics of Guinea Pig IgE
- 1 January 1976
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 51 (4), 416-428
- https://doi.org/10.1159/000231616
Abstract
Anti-dinitrophenyl (DNP) IgE antibody was produced in guinea pigs (GP) by immunization and repeated boosters with 1 μ g DNP-Ascaris extract in Al(OH)3. The isoelectric point was determined to be 6.48 and the molecular weight to be 185,000 daltons. In absorbtion chromatography, rabbit anti-GPIgG1 could not absorb the anaphylactic activity of the IgE. The activity of IgE was destroyed by heating at 56 °C for 1 h. IgE persisted in the skin for at least 3 weeks.This publication has 10 references indexed in Scilit:
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