Relative Dehydrogenase Activity of Kidney and Liver Slices from Control and Tumor Mice.

Abstract

The in vitro dehydrogenase activity of liver and kidney slices from female control and tumor mice of the CFW, C3H, DBA, and A strains was detd. and the relative intensity of the kidney to liver values (K/L ratio) was calculated. The K/L ratio was found to be maintained within a narrow range in the different control groups. In the CFW and A mice this value was shifted to a lower value in the presence of a tumor. Such a change occurred to a lesser degree in DBA mice and not at all in the C3H mice.