Disseminated Pulmonary Calcification

Abstract

ANTIGEN skin testing in the presence of disseminated pulmonary calcification shows a high prevalence of histoplasmin sensitivity. Furcolow et al.,¹ in a combined study using tuberculin and histoplasmin antigen and x-ray examination of thousands of persons, begun in 1945 in Kansas City, Missouri, brought out the striking relation between calcifications seen on the roentgenograms and parallel skin sensitivity to the antigen. Table 1 illustrates the calcification-antigen relation observed in the Kansas City study.Previous reports by Christie and Peterson² and Palmer³ called attention to the frequency of histoplasmin sensitivity among negative tuberculin reactors whose films show disseminated pulmonary calcification. Palmer⁴ also pointed . . .