The distribution of ascorbic acid between the particulate and non-particulate components of adrenal and liver cells

Abstract

Estimations were made of the ascorbic acid content of the particulate and non-particulate fractions of cytoplasm separated by high-speed centrifugation of sucrose dispersions of ox adrenal medulla and cortex, and of dog liver. The ascorbic acid was found to be entirely or almost entirely in the non-particulate fraction. These results are discussed and additional evidence is advanced for considering that the location of reduced silver particles does not necessarily indicate the localization of ascorbic acid within the cell.