The retarding effect of allyl thiourea and of partial thyroidectomy at birth upon learning in the rat.
- 1 January 1946
- journal article
- research article
- Published by American Psychological Association (APA) in Journal of Comparative Psychology
- Vol. 39 (6), 359-370
- https://doi.org/10.1037/h0053557
Abstract
Learning was retarded in normal male rats of two different age groups (190 and 375 days old) through daily injns. of 20-25 mg. of the thyroid-depressant drug, allyl thiourea. The injd. rats made more daily errors, but did not require significantly longer time to make the daily run. Learning was impaired in rats which had been partially thyroidecto-mized at birth. These hypothyroid rats also made a greater number of daily errors but required no longer to run through the maze. A multiple-discrimination (visual) problem was used, and the motivation employed was escape from cold (9-15 [degree]C) water through which the animals were forced to run.Keywords
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