The Action of Cytostatic Agents on the Chromosomes of Human Leukocytes in Vitro (Preliminary Communication)
Open Access
- 1 June 1966
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 27 (6), 816-823
- https://doi.org/10.1182/blood.v27.6.816.816
Abstract
Quantitative analysis of the chromosomal injuries following in vitro addition of various cytostatic agents to short-term human leukocyte cultures was carried out. The data obtained suggest that the cytogenic action of these various compounds in vitro follows a pattern similar to its action when administered therapeutically to man. The technics used may form the basis of further evaluation of the cytogenetic activity of these various compounds.This publication has 4 references indexed in Scilit:
- Strukturanomalien der chromosomen menschlicher leukozyten in vitro durch triaethylenmelaminExperimental Cell Research, 1965
- EFFECTS OF MITOMYCIN C ON HUMAN CHROMOSOMESThe Journal of cell biology, 1964
- EFFECTS OF FLUORODEOXYURIDINE ON DNA REPLICATION, CHROMOSOME BREAKAGE, AND REUNIONProceedings of the National Academy of Sciences, 1962
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960