Propagation of Canine Distemper Virus in Suckling Hamsters

Abstract
The Lederle strain of chick embryo adapted distemper virus was propagated in suckling hamsters through 16 serial transfers. The virus elicited a lethal infection in this host in 4-7 days following inoculation. Proof of the identity of the hamster propagated agent was derived from serum neutralization tests in hamsters and from the successful immunization of ferrets.