Interactions among Drugs for HIV and Opportunistic Infections

Abstract

Drug interactions are an important factor in the treatment of patients with human immunodeficiency virus (HIV) infection. The complexity of current drug regimens for such patients requires that clinicians recognize and manage drug interactions. Antiretroviral drug regimens typically consist of three or four antiretroviral drugs but may include even more. In addition, patients may receive other drugs for supportive care, treatment of opportunistic infections, and immunomodulation, as well as alternative drugs obtained from health care providers other than their primary provider. Drug interactions are often unavoidable in HIV-infected patients because of the drug classes involved and the number of drugs . . .