Prevalence of antibody to the hepatitis A virus in a large institution for the mentally retarded
- 1 January 1978
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 2 (4), 335-339
- https://doi.org/10.1002/jmv.1890020406
Abstract
The prevalence of antibody to hepatitis A virus (anti‐HAV) was determined in 854 people living in a large institution for the mentally retarded in Melbourne. Altogether 638 (74.4%) of the subjects were found to have specific antibody detectable by solid‐phase radioimmunoassay (SPRIA). No difference in antibody prevalence was observed between males and females; however, the prevalence was higher among subjects with Down syndrome (84.1%) than those of other forms of mental retardation (72.8%). In both groups there was an increase in prevalence of antibody with increasing age and duration of institutionalization. When compared with the open community, patients in this Institution have a higher prevalence of antibody and appear to acquire their infections at an earlier age.Keywords
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