Synthesis of Polysubstituted Aromatic Acids Using an Intramolecular Benzyne Cyclisation
- 1 May 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (10), 1423-1436
- https://doi.org/10.1080/00397919008052858
Abstract
The protected haloanilines 3 and 4 undergo base catalysed elimination of halide to give aryne intermediates. These serve as useful precursors for the synthesis of the aromatic acids 7 and 8.Keywords
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