Calcium and Age in Fibroblasts from Control Subjects and Patients with Cystic Fibrosis
- 23 April 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4544), 417-419
- https://doi.org/10.1126/science.7071590
Abstract
Intracellular calcium increases significantly as human fibroblasts age in culture. The calcium increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts from subjects with cystic fibrosis in comparison with cells from control subjects. Intracellular calcium, which is thought to be a pathogenetic factor in cystic fibrosis, may also be a meaningful marker in cell aging.This publication has 14 references indexed in Scilit:
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