The biochemistry of aromatic amines. 8. Synthesis and detection of di-(2-amino-1-naphthyl) hydrogen phosphate, a metabolite of 2-naphthylamine in dogs

Publisher Website
Google Scholar
Abstract
Di(2-amino-1-naphthyl) hydrogen phosphate has been synthesized by catalytic reduction of di(2-nitro-1-naphthyl) hydrogen phosphate. The compound has been detected in the urine of dogs dosed with 2-naphthylamine. The dog urine also contains 2-amino- 1-naphthyl hydrogen sulphate, 2-naphthylamine, 2-amino-1-naphthyl glucosiduronic acid, 2-amino-6-naphthyl hydrogen sulphate and 2-amino-6-naphthyl glucosiduronic acid.