ADDISON'S DISEASE AND PEPTIC ULCER
- 1 October 1955
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 15 (10), 1300-1307
- https://doi.org/10.1210/jcem-15-10-1300
Abstract
A 49-year-old negro housewife with Addison''s disease is described, in whom a gastric ulcer developed during treatment with 25 mg of corti-sone acetate daily. It is suggested that adrenal hormone is neces-sary for, but not the cause of the development of peptic ulcer, and that in the presence of an excess of adrenal hormone the stomach and/or duodenum may be sensitized to respond by secre-tory hyperactivity and/or ulceration to stimuli which would ordinarily be innocuous.Keywords
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