Rapid Tranquilization: A Reevaluation
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Neuropsychobiology
- Vol. 22 (2), 90-96
- https://doi.org/10.1159/000118598
Abstract
Years of experience have indicated that the widespread and frequent use of rapid tranquilization is not based on demonstrated efficacy. Multiple high-dose administration of neuroleptics parenterally does not produce rapid relief of psychosis and, at the same time, exposes the patient to risk of severe side effects. Rapid tranquilization may only have a limited and specific applicability; therefore, it is important to reexamine its clinical indications and to search for safer alternatives.Keywords
This publication has 9 references indexed in Scilit:
- Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of PsychosesArchives of General Psychiatry, 1988
- CLINICAL EFFECTIVENESS OF ORAL AND PARENTERAL RAPID NEUROLEPTIZATION1987
- Dissimilar dosing with high-potency and low-potency neurolepticsAmerican Journal of Psychiatry, 1984
- Minimal maintenance medication: Effects of three dose schedules on relapse rates and symptoms in chronic schizophrenic outpatientsComprehensive Psychiatry, 1983
- Rapid Treatment of Acute Psychotic Symptoms With High- and Low-Dose HaloperidolArchives of General Psychiatry, 1981
- Neuroleptic malignant syndromeNeurology, 1981
- Acute high-dose parenteral haloperidol treatment of psychosisAmerican Journal of Psychiatry, 1979
- Overview: efficacy and safety of the rapid neuroleptization method with injectable haloperidolAmerican Journal of Psychiatry, 1979
- Large Doses of Chlorpromazine in the Treatment of Psychiatric Patients1955