H2-receptors and traumatic oedema
- 1 August 1978
- journal article
- research article
- Published by Wiley in The Journal of Pathology
- Vol. 125 (4), 201-204
- https://doi.org/10.1002/path.1711250405
Abstract
The effects of the H2-antagonists metiamide and cimetidine on edema following limb ischemia or scald were investigated in 2 rat strains. No inhibition of edema formation was found except when large doses of cimetidine were given before scalding. This effect was attributed to the fall in body temperature. The view that H2-receptors are concerned in the vascular response to injury was not supported.This publication has 12 references indexed in Scilit:
- Regional vascular resistance and heart rate responses mediated through H1- and H2-histamine receptors in the unanaesthetised rabbitEuropean Journal of Pharmacology, 1977
- H1- and H2-Histamine Receptor Antagonists and Protection against Traumatic ShockExperimental Biology and Medicine, 1977
- Histamine H2-receptor antagonists and thermal injury in ratsBurns, 1976
- HISTAMINE RECEPTORS IN PERIPHERAL VASCULAR BEDS IN THE CATBritish Journal of Pharmacology, 1975
- AN ANALYSIS OF THE DEPRESSOR RESPONSES TO HISTAMINE IN THE CAT AND DOG: INVOLVEMENT OF BOTH H1‐ AND H2‐RECEPTORSBritish Journal of Pharmacology, 1975
- Definition and Antagonism of Histamine H2-receptorsNature, 1972
- Urethane Hyperglycæmia and Hypothalamic ActivationNature, 1964
- Vascular reactions to histamine, histamine‐liberator and leukotaxine in the skin of guinea‐pigsThe Journal of Physiology, 1952
- The effect of local temperature on fluid loss in thermal burnsThe Journal of Physiology, 1946
- Experimental Chemotherapy of Burns and Shock. IV. Production of Traumatic Shock in Mice. V. Therapy with Mouse Serum and Sodium SaltsPublic Health Reports®, 1943