INHIBITION OF THE ENZYMIC OXIDATION OF DPNH BY STER HORMONES
- 1 December 1959
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 45 (12), 1730-1739
- https://doi.org/10.1073/pnas.45.12.1730
Abstract
Low concentrations of a large number of steroid hormones and diethylstilbestrol inhibited reduced diphosphopyridine nucleotide (DPNH) oxidation by enzyme preparations from both mammalian and microbial sources. Neither reduced triphosphopyridine nucleotide (TPNH) or succinate were similarly affected, however. In skeletal muscle, the site of steroid inhibition proved to be the DPNH-cytochrome c reductase reaction. a-Tocopherol and other compounds could competitively reverse the steroid effect.This publication has 22 references indexed in Scilit:
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