Argatroban analogs: Synthesis, thrombin inhibitory activity and cell permeability of aminoheterocyclic guanidine surrogates
- 22 September 1994
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 4 (18), 2165-2170
- https://doi.org/10.1016/s0960-894x(00)80064-5
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profileTrends in Pharmacological Sciences, 1993
- Refined 2·3ÅX-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA: A starting point for improving antithromboticsJournal of Molecular Biology, 1992
- Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell lineGastroenterology, 1992
- Chapter 11. Future Antithrombotic TherapyPublished by Elsevier ,1992
- A Strategy for a Rational Approach to Designing Synthetic Selective InhibitorsSeminars in Thrombosis and Hemostasis, 1992
- BINDING MECHANISMS OF THROMBIN INHIBITORS AND TRYPSIN INHIBITORS REVEALED BY X-RAY CRYSTALLOGRAPHYAnalytical Sciences, 1991
- Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal MucosaPharmaceutical Research, 1990
- Preparation and Properties of Nalpha-Di-tert-Butoxycarbonyl Amino Acids. Applicability in the Synthesis of Leu-Enkephalin.Acta Chemica Scandinavica, 1990
- Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial PermeabilityGastroenterology, 1989
- Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portionBiochemical and Biophysical Research Communications, 1981