Zur Kenntnis des Plasmalogens IV. Mitteilung Eine neuartige Gruppe von Phosphatiden [Acetalphosphatide]

Abstract

Plasmalogen was isolated by saponification of beef phosphatides with KOH and precipitation of the fatty acids with brucine acetate. On treating the ppt. with acetone, 2 fractions of plasmalogen were obtained which differed by their solubility in acetone. The soluble part was called plasmalogenic acid and could be isolated as the Li salt. The ratio of the insoluble plasmalogen to the plasmalogenic acid depended on the degree of the hydrolysis, which led to the assumption that the plasmalogenic acid was a secondary hydrolysis product of the plasmalogen. The constitution of the acid was similar to that of the phosphatidic acids. Plasmalogen as well as its acid was a heterogeneous mixture of 2 isomers ([alpha]- and [beta]-form), of homologues (stearic and palmitic), and probably of saturated and unsaturated aldehydes.