Growth Hormone in Uremia I. Plasma Growth Hormone, Insulin and Glucagon after Oral and Intravenous Glucose in Uremic Subjects

Abstract

Sixteen uremics with normal fasting blood glucose were studied. Abnormal glucose tolerance was a frequent finding. The initial insulin response to glucose was normal. Ten out of the 15 uremics studied with oral glucose exhibited a paradoxical rise in serum growth hormone. These uremics were significantly more intolerant to glucose than their counterpart with normal growth hormone response.